Insomnia due to hypertriglyceridemia can be treated by rosuvastatin/ezetimibe

Abstract Funding Acknowledgements Type of funding sources: None. Background Metabolic syndrome associated with elevated fasting triglyceridemia (TG) is often insomnia. The new guidelines ESC for dyslipidemia advice the statin and/or ezetimibe treatment like fist line therapy in patients hypertriglyceridemia, also before then fibrates or omega 3. We examined impact rosuvastatin/ezetimibe reduction insomnia patents hypertriglyceridemia. Methods In this study was enrolled a group 148 hypertriglyceridemia and Patients were screened severe insomnia, defined by score four more on three Hamilton Depression Rating Scale (HDRS) sleep items, HTG characterized TG≥200mg/dL. duration evaluated smartwatch every 7 days. Mean age 61,12 years. All patient admitted ambulatory cardiology wash out dyslipidaemic syndrome. all we added 20 mg rosuvastatin plus 10 daily to reassessed after 30 Results Rosuvastatin/ezetimibe effective as add-on . treated reported an improvement symptoms. After days, disappeared 69% reduced 21% patients. number sleeping hours improved from 5:35 min 7:25 minutes. Therapy well tolerated 99% patents, stopped only 2 cases. Conclusions Our initial experience suggests that may play role